Isolated Skull Defect

Figure epid_18a_n.jpg and epid_18b_n.jpg: In schoolchildren with one, two or more smooth mass (es) painful on pressure near or lateral to the midline, or in skull defects with an irregular defect without a sclerotic border, and recognized incidentally, an eosinophilic granuloma is an important differential diagnosis. Figure epid_18a_n.jpg: Skull x-ray of a 10.8-year-old girl with an occipital oval skull defect above the bony impression of sinus confluence, which corresponds to a single focus of an eosinophilic granuloma. Figure epid_18b_n.jpg: The operative findings show a yellow mass within a skull defect corresponding to an eosinophilic granuloma. Surgery performed following work-up examinations in a center is in case of a single focus not only diagnostic, but also therapeutic (often category 3a, possible is 4, and rarely 5).